The Bioscreen C Automated Microbiology Growth Curve Analysis System directly measures microorganism growth. As microorganisms grow, they increase the turbidity of their growth medium. By measuring the turbidity of this medium over time, an optical density (O.D.) curve can be generated. The curve reflects the growth (increased concentration) of the organism of interest.

Click here for the Bioscreen C data sheet.

Honeycomb Microplate
The organism of interest and any growth medium are manually dispensed using a multichannel pipette into wells of a special honeycomb microplate. This 10 x 10 well plate is designed to provide a uniform temperature across each of the 100 wells in the plate. A fitted plate lid with special characteristics eliminates troublesome condensation and evaporation, which often interferes with O.D. readings with conventional 96-well plates.

Bioscreen C Analyzer
The instrument has a unique incubator incorporating a liquid circulation heat exchanger which provides constant temperatures to all wells. This is essential for developing high quality growth curves. It also includes a linear shaker to assure good mixing in each well.

It has a sensitive reader that measures turbidity, a technique more sensitive than a spectrophotometer. The reader is also equipped with 8 filters to measure specific wavelengths. Two covered honeycomb plates may be run at one time, making it possible to run 200 samples simultaneously.

Turbidometric measurements are made kinetically during the course of the run. Data is exported to a PC, and subsequently processed to generate growth curves, plotting O.D. vs. time.

Software
Bioscreen EZ Experiment software is provided free with the system. In addition, Norden Logic Oy has developed new commercial software with the advanced features that Bioscreen customers asked for.

For more information, click here or on the "Software" tab.

Bioscreen-C 10-Channel Adjustable Voyager™ Electronic Pipetting System, available separately, speeds sample transfers from 96-well plates and labware of different sizes to Bioscreen’s honeycomb microplates. Users can change the pipettor’s tip spacing on the fly. A simple push of a button on the Touch Wheel interface opens or closes the tips to a spacing defined by the user.

Click here for the Voyager™ data sheet.